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| also: | ECAC Upstate Independent |
| Year | Seed | Record | Finishing Round | Coach |
| 1957 | - | 2 - 1 | Elite Eight (3rd rd) | Marc Guley |
| 1966 | - | 1 - 1 | Elite Eight (3rd rd) | Fred Lewis |
| 1973 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Roy Danforth |
| 1974 | - | 0 - 1 | Round of 32 (1st rd) | Roy Danforth |
| 1975 | - | 3 - 2 | National Semifinals (4th rd) | Roy Danforth |
| 1976 | - | 0 - 1 | Round of 32 (1st rd) | Roy Danforth |
| 1977 | - | 1 - 1 | Sweet Sixteen (2nd rd) | Jim Boeheim |
| 1978 | - | 0 - 1 | Round of 32 (1st rd) | Jim Boeheim |
| 1979 | 4 | 1 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 1980 | 1 | 1 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 1983 | 6 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 1984 | 3 | 1 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 1985 | 7 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 1986 | 2 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 1987 | 2 | 5 - 1 | National Championship (6th rd) | Jim Boeheim |
| 1988 | 3 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 1989 | 2 | 3 - 1 | Elite Eight (4th rd) | Jim Boeheim |
| 1990 | 2 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 1991 | 2 | 0 - 1 | Round of 64 (1st rd) | Jim Boeheim |
| 1992 | 6 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 1994 | 4 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 1995 | 7 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 1996 | 4 | 5 - 1 | National Championship (6th rd) | Jim Boeheim |
| 1998 | 5 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 1999 | 8 | 0 - 1 | Round of 64 (1st rd) | Jim Boeheim |
| 2000 | 4 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 2001 | 5 | 1 - 1 | Round of 32 (2nd rd) | Jim Boeheim |
| 2003 | 3 | 6 - 0 | National Championship (6th rd) | Jim Boeheim |
| 2004 | 5 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 2005 | 4 | 0 - 1 | Round of 64 (1st rd) | Jim Boeheim |
| 2006 | 5 | 0 - 1 | Round of 64 (1st rd) | Jim Boeheim |
| 2009 | 3 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
| 2010 | 1 | 2 - 1 | Sweet Sixteen (3rd rd) | Jim Boeheim |
