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| also: | Atlantic Ten Independent |
| Year | Seed | Record | Finishing Round | Coach |
| 1939 | - | 1 - 1 | National Semifinals (2nd rd) | Alex Severance |
| 1949 | - | 1 - 1 | Elite Eight (1st rd) | Alex Severance |
| 1951 | - | 0 - 1 | Sweet Sixteen (1st rd) | Alex Severance |
| 1955 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Alex Severance |
| 1962 | - | 2 - 1 | Elite Eight (3rd rd) | Jack Kraft |
| 1964 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Jack Kraft |
| 1969 | - | 0 - 1 | Round of 32 (1st rd) | Jack Kraft |
| 1970 | - | 2 - 1 | Elite Eight (3rd rd) | Jack Kraft |
| 1971 | - | 4 - 1 | National Championship (5th rd) | Jack Kraft |
| 1972 | - | 1 - 2 | Sweet Sixteen (2nd rd) | Jack Kraft |
| 1978 | - | 2 - 1 | Elite Eight (3rd rd) | Rollie Massimino |
| 1980 | 8 | 1 - 1 | Round of 32 (2nd rd) | Rollie Massimino |
| 1981 | 9 | 1 - 1 | Round of 32 (2nd rd) | Rollie Massimino |
| 1982 | 3 | 2 - 1 | Elite Eight (4th rd) | Rollie Massimino |
| 1983 | 3 | 2 - 1 | Elite Eight (4th rd) | Rollie Massimino |
| 1984 | 7 | 1 - 1 | Round of 32 (2nd rd) | Rollie Massimino |
| 1985 | 8 | 6 - 0 | National Championship (6th rd) | Rollie Massimino |
| 1986 | 10 | 1 - 1 | Round of 32 (2nd rd) | Rollie Massimino |
| 1988 | 6 | 3 - 1 | Elite Eight (4th rd) | Rollie Massimino |
| 1990 | 12 | 0 - 1 | Round of 64 (1st rd) | Rollie Massimino |
| 1991 | 9 | 1 - 1 | Round of 32 (2nd rd) | Rollie Massimino |
| 1995 | 3 | 0 - 1 | Round of 64 (1st rd) | Steve Lappas |
| 1996 | 3 | 1 - 1 | Round of 32 (2nd rd) | Steve Lappas |
| 1997 | 4 | 1 - 1 | Round of 32 (2nd rd) | Steve Lappas |
| 1999 | 8 | 0 - 1 | Round of 64 (1st rd) | Steve Lappas |
| 2005 | 5 | 2 - 1 | Sweet Sixteen (3rd rd) | Jay Wright |
| 2006 | 1 | 3 - 1 | Elite Eight (4th rd) | Jay Wright |
| 2007 | 9 | 0 - 1 | Round of 64 (1st rd) | Jay Wright |
| 2008 | 12 | 2 - 1 | Sweet Sixteen (3rd rd) | Jay Wright |
| 2009 | 3 | 4 - 1 | National Semifinals (5th rd) | Jay Wright |
| 2010 | 2 | 1 - 1 | Round of 32 (2nd rd) | Jay Wright |
