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| also: | Big East Great Midwest Independent |
| Year | Seed | Record | Finishing Round | Coach |
| 1955 | - | 2 - 1 | Elite Eight (3rd rd) | Jack Nagle |
| 1959 | - | 1 - 2 | Sweet Sixteen (2nd rd) | Eddie Hickey |
| 1961 | - | 0 - 1 | Round of 32 (1st rd) | Eddie Hickey |
| 1968 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Al McGuire |
| 1969 | - | 2 - 1 | Elite Eight (3rd rd) | Al McGuire |
| 1971 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Al McGuire |
| 1972 | - | 1 - 2 | Sweet Sixteen (2nd rd) | Al McGuire |
| 1973 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Al McGuire |
| 1974 | - | 4 - 1 | National Championship (5th rd) | Al McGuire |
| 1975 | - | 0 - 1 | Round of 32 (1st rd) | Al McGuire |
| 1976 | - | 2 - 1 | Elite Eight (3rd rd) | Al McGuire |
| 1977 | - | 5 - 0 | National Championship (5th rd) | Al McGuire |
| 1978 | - | 0 - 1 | Round of 32 (1st rd) | Hank Raymonds |
| 1979 | 3 | 1 - 1 | Sweet Sixteen (3rd rd) | Hank Raymonds |
| 1980 | 9 | 0 - 1 | Round of 64 (1st rd) | Hank Raymonds |
| 1982 | 7 | 1 - 1 | Round of 32 (2nd rd) | Hank Raymonds |
| 1983 | 9 | 0 - 1 | Round of 64 (1st rd) | Hank Raymonds |
| 1993 | 12 | 0 - 1 | Round of 64 (1st rd) | Kevin O'Neill |
| 1994 | 6 | 2 - 1 | Sweet Sixteen (3rd rd) | Kevin O'Neill |
| 1996 | 4 | 1 - 1 | Round of 32 (2nd rd) | Mike Deane |
| 1997 | 7 | 0 - 1 | Round of 64 (1st rd) | Mike Deane |
| 2002 | 5 | 0 - 1 | Round of 64 (1st rd) | Tom Crean |
| 2003 | 3 | 4 - 1 | National Semifinals (5th rd) | Tom Crean |
| 2006 | 7 | 0 - 1 | Round of 64 (1st rd) | Tom Crean |
| 2007 | 8 | 0 - 1 | Round of 64 (1st rd) | Tom Crean |
| 2008 | 6 | 0 - 1 | Round of 32 (2nd rd) | Tom Crean |
| 2009 | 6 | 1 - 1 | Round of 32 (2nd rd) | Buzz Williams |
| 2010 | 6 | 0 - 1 | Round of 64 (1st rd) | Buzz Williams |
