Southern California NCAA Tournament Results
Tournament Record: 12 - 17
Current Conference: Pacific Ten
| Year | Seed | Record | Finishing Round | Coach |
| 1940 | - | 1 - 1 | National Semifinals (2nd rd) | Sam Barry |
| 1954 | - | 2 - 2 | National Semifinals (4th rd) | Forrest Twogood |
| 1960 | - | 0 - 1 | Round of 32 (1st rd) | Forrest Twogood |
| 1961 | - | 1 - 2 | Sweet Sixteen (2nd rd) | Forrest Twogood |
| 1979 | 7 | 1 - 1 | Round of 32 (2nd rd) | Bob Boyd |
| 1982 | 9 | 0 - 1 | Round of 64 (1st rd) | Stan Morrison |
| 1985 | 8 | 0 - 1 | Round of 64 (1st rd) | Stan Morrison |
| 1991 | 10 | 0 - 1 | Round of 64 (1st rd) | George Raveling |
| 1992 | 2 | 1 - 1 | Round of 32 (2nd rd) | George Raveling |
| 1997 | 11 | 0 - 1 | Round of 64 (1st rd) | Henry Bibby |
| 2001 | 6 | 3 - 1 | Elite Eight (4th rd) | Henry Bibby |
| 2002 | 4 | 0 - 1 | Round of 64 (1st rd) | Henry Bibby |
| 2007 | 5 | 2 - 1 | Sweet Sixteen (3rd rd) | Tim Floyd |
| 2008 | 6 | 0 - 1 | Round of 64 (1st rd) | Tim Floyd |
| 2009 | 10 | 1 - 1 | Round of 32 (2nd rd) | Tim Floyd |
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